Application of antibacterial coatings on resin composite implant materials using inkjet printing technology
: Wickström Henrika, Anthoni Annette, Palo Mirja, Nyman Johan O., Määttänen Anni, Nurmi Mari, Moritz Niko, Oja Terhi, Preis Maren, Sandler Niklas
: International Conference on Digital Printing Technologies
Publisher: Society for Imaging Science and Technology
: 2016
: Printing for Fabrication 2016 (NIP32): 32nd International Conference on Digital Printing Technologies, NIP 2016
: International Conference on Digital Printing Technologies
: 89
: 93
: 5
: 978-0-89208-322-0
: 2169-4362
: http://www.ingentaconnect.com/contentone/ist/nipdf/2016/00002016/00000001/art00026#expand/collapse
Fiber-reinforced composite (FRC) implants have shown to be a favorable option as an implant material, compared to titanium, in terms of biocompatibility and mechanical properties. Furthermore, application of antibacterial coatings onto these implant material have been presented as a viable strategy to prevent biofilm formation. The purpose of this study was to analyse the biofilm prevention effect on gentamicin coated fiber-reinforced composite implants, by means of inkjet technology, when exposed to Staphylococcus aureus ATCC 25923 bacteria. Scanning white light interferometry and scanning electron microscopy were used to characterize the surface texture and surface roughness of the pure and printed implant material and titanium (control) specimens. Quantification of the deposited gentamicin amount was performed using a colorimetric assay. Statistically significant biofilm inhibition was seen for the gentamicin coated resin specimens and a more than 100-fold reduction in viable cells was determined. It was concluded that piezoelectric inkjet technology could be a viable technology to precisely deposit anti-biofilm coatings onto implant materials. The presented work is based on results of a master's thesis by Anthoni et al., 2016 conducted at Åbo Akademi University [1].