A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä

Hospital admissions for lower respiratory tract infections in children born moderately/late preterm




TekijätPaula Haataja, Päivi Korhonen, Riitta Ojala, Mikko Hirvonen, Matti Korppi, Mika Gissler, Tiina Luukkaala, Outi Tammela

KustantajaJohn Wiley and Sons Inc.

Julkaisuvuosi2018

JournalPediatric Pulmonology

Tietokannassa oleva lehden nimiPediatric Pulmonology

Vuosikerta53

Numero2

Aloitussivu209

Lopetussivu217

Sivujen määrä9

ISSN8755-6863

DOIhttps://doi.org/10.1002/ppul.23908

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/29612038


Tiivistelmä

Objective: To evaluate the frequency and predictors of hospital admissions for lower respiratory tract infections (LRTIs) in moderately preterm (MP, 32+0 to 33+6 weeks) and late preterm (LP, 34+0 to 36+6 weeks) infants compared to term (T ≥37 weeks) and very preterm (VP, <32+0 weeks) infants.

Study Design: This national register‐based study covered all infants born in Finland in 1991‐2008. Data on 1 018 256 infants were analyzed in four gestational age‐based groups: VP (n = 6329), MP (n = 6796), LP (n = 39 928), and T (n = 965 203) groups. Data on hospital admissions due to bronchiolitis/bronchitis and pneumonia were collected up to the age of 7 years.

Results: Hospital admissions for LRTIs were more common in the MP and LP groups than in the T group but less frequent than in the VP group: bronchiolitis/bronchitis (VP 24.4%, MP 13.9%, LP 9.5%, and T 5.6%) and pneumonia (VP 8.8%, MP 4.5%, LP 3.3%, and T 2.4%). Compared to the term group, MP and LP birth predicted bronchiolitis/bronchitis (MP OR 1.89; 95%CI 1.75‐2.03, LP 1.51; 1.45‐1.56) and pneumonia (MP 1.49; 1.32‐1.67, LP 1.25; 1.18‐1.33) admissions. Statistically significant risk factors for LRTIs included maternal smoking, cesarean section, male sex, admission to a neonatal unit and ventilator therapy. In addition, being first‐born, being born SGA and neonatal antibiotic therapy were associated with bronchiolitis/bronchitis.

Conclusions: MP and LP births, in addition to VP birth, have a significant impact on respiratory infectious morbidity and the need of hospital admissions for LRTIs.


Ladattava julkaisu

This is an electronic reprint of the original article.
This reprint may differ from the original in pagination and typographic detail. Please cite the original version.




Ladattava julkaisu

This is an electronic reprint of the original article.
This reprint may differ from the original in pagination and typographic detail. Please cite the original version.





Last updated on 2024-26-11 at 12:15