A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Workflow assessing the effect of gait alterations on stresses in the medial tibial cartilage - combined musculoskeletal modelling and finite element analysis
Tekijät: K. S. Halonen, C. M. Dzialo, M. Mannisi, M. S. Venäläinen, M. de Zee, M. S. Andersen
Kustantaja: NATURE PUBLISHING GROUP
Julkaisuvuosi: 2017
Journal: Scientific Reports
Tietokannassa oleva lehden nimi: SCIENTIFIC REPORTS
Lehden akronyymi: SCI REP-UK
Artikkelin numero: 17396
Vuosikerta: 7
Sivujen määrä: 14
ISSN: 2045-2322
DOI: https://doi.org/10.1038/s41598-017-17228-x
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/Publication/28907560
Knee osteoarthritis (KOA) is most common in the medial tibial compartment. We present a novel method to study the effect of gait modifications and lateral wedge insoles (LWIs) on the stresses in the medial tibial cartilage by combining musculoskeletal (MS) modelling with finite element (FE) analysis. Subject's gait was recorded in a gait laboratory, walking normally, with 5 degrees and 10 degrees LWIs, toes inward ('Toe in'), and toes outward ('Toe out wide'). A full lower extremity MRI and a detailed knee MRI were taken. Bones and most soft tissues were segmented from images, and the generic bone architecture of the MS model was morphed into the segmented bones. The output forces from the MS model were then used as an input in the FE model of the subject's knee. During stance, LWIs failed to reduce medial peak pressures apart from Insole 10 degrees during the second peak. Toe in reduced peak pressures by -11% during the first peak but increased them by 12% during the second. Toe out wide reduced peak pressures by -15% during the first and increased them by 7% during the second. The results show that the work flow can assess the effect of interventions on an individual level. In the future, this method can be applied to patients with KOA.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
