B1 Vertaisarvioimaton kirjoitus tieteellisessä lehdessä
Synthesis of oligonucleotide analogues by using phosphoramidite reagents derived from 2,2-bis(hydroxymethyl)malonates
Tekijät: Guzaev A, Salo H, Azhayev A, Lonnberg H
Kustantaja: INST ORGANIC CHEM AND BIOCHEM
Julkaisuvuosi: 1996
Lehti:: Collection of Czechoslovak Chemical Communications
Tietokannassa oleva lehden nimi: COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS
Lehden akronyymi: COLLECT CZECH CHEM C
Vuosikerta: 61
Aloitussivu: S226
Lopetussivu: S229
Sivujen määrä: 4
ISSN: 0010-0765
Tiivistelmä
A new family of non-nucleosidic phospharamidite rt agents derived from either esters or amides of 2,2-bis(hydroxymethyl)malonic acid is described. The utility of the building blocks 1-5 ii demonstrated by preparation of 5'-phosphorylated oligonucleotides as well as hydrophobic, polyamino and fluorescent labelled oligonucleotide analogues.
A new family of non-nucleosidic phospharamidite rt agents derived from either esters or amides of 2,2-bis(hydroxymethyl)malonic acid is described. The utility of the building blocks 1-5 ii demonstrated by preparation of 5'-phosphorylated oligonucleotides as well as hydrophobic, polyamino and fluorescent labelled oligonucleotide analogues.
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