A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity
Tekijät: Kemppainen KM, Vehik K, Lynch KF, Larsson HE, Canepa RJ, Simell V, Koletzko S, Liu E, Simell OG, Toppari J, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian WA, She JX, Akolkar B, Schatz DA, Atkinson MA, Blaser MJ, Krischer JP, Hyöty H, Agardh D, Triplett EW; Environmental Determinants of Diabetes in the Young (TEDDY) Study Group
Julkaisuvuosi: 2017
Journal: JAMA Pediatrics
Vuosikerta: 171
Numero: 12
Aloitussivu: 1217
Lopetussivu: 1225
Sivujen määrä: 9
ISSN: 2168-6203
DOI: https://doi.org/10.1001/jamapediatrics.2017.2905
Conclusions and Relevance The use of the most prescribed antibiotics during the first 4 years of life, regardless of geographic region, was not associated with the development of autoimmunity for T1D or CD. These results suggest that a risk of islet or tissue transglutaminase autoimmunity need not influence the recommendations for clinical use of antibiotics in young children at risk for T1D or CD
