A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Early presentation of osteonecrosis in acute lymphoblastic leukemia: Two children from the Nordic and Baltic cohort
Tekijät: Mogensen SS, Harila-Saari A, Frandsen TL, Lahteenmaki P, Castor A, Kohonen I, Schmiegelow K, Makitie O
Kustantaja: WILEY
Julkaisuvuosi: 2017
Journal: Pediatric Blood and Cancer
Tietokannassa oleva lehden nimi: PEDIATRIC BLOOD & CANCER
Lehden akronyymi: PEDIATR BLOOD CANCER
Artikkelin numero: ARTN e26624
Vuosikerta: 64
Numero: 11
Sivujen määrä: 4
ISSN: 1545-5009
eISSN: 1545-5017
DOI: https://doi.org/10.1002/pbc.26624
Tiivistelmä
Osteonecrosis (ON) is usually considered treatment related in patients with acute lymphoblastic leukemia (ALL). We report two patients with presentation of ON at the time of ALL diagnosis. Both were females and diagnosed with ALL at age 8 and 14 years. In the latter, some symptoms and radiologically verified ON in both knees were still present after the end of ALL therapy. No pediatric patients have previously been reported with ON presenting before initiation of ALL therapy.
Osteonecrosis (ON) is usually considered treatment related in patients with acute lymphoblastic leukemia (ALL). We report two patients with presentation of ON at the time of ALL diagnosis. Both were females and diagnosed with ALL at age 8 and 14 years. In the latter, some symptoms and radiologically verified ON in both knees were still present after the end of ALL therapy. No pediatric patients have previously been reported with ON presenting before initiation of ALL therapy.
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