A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä

Synthesis of enantiopure structured triacylglycerols




TekijätBjörn Kristinsson, Kaisa M. Linderborg, Heikki Kallio, Gudmundur G. Haraldsson

Julkaisuvuosi2014

JournalTetrahedron: Asymmetry

Tietokannassa oleva lehden nimiTetrahedron Asymmetry

Vuosikerta25

Numero2

Aloitussivu125

Lopetussivu132

Sivujen määrä8

ISSN0957-4166

DOIhttps://doi.org/10.1016/j.tetasy.2013.11.015

Verkko-osoitehttp://api.elsevier.com/content/abstract/scopus_id:84893057235


Tiivistelmä

The synthesis of nine enantiopure structured triacylglycerols (TAGs) of the AAB type is described, all possessing the (S)-absolute configuration. Six of them possess one saturated and two identical unsaturated fatty acyl chains, whereas the remaining three possess two identical saturated fatty acids along with one unsaturated fatty acid. The former group was synthesized by a five-step chemoenzymatic route involving a highly regioselective immobilized Candida antarctica lipase, starting from enantiopure (R)-solketal. The second group was prepared by a fully chemical five-step approach based on the same chiral precursor. Such enantiopure TAGs are strongly required as standards for the enantiospecific analysis of intact TAGs in fats and oils. © 2013 Elsevier Ltd. All rights reserved.




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