B1 Vertaisarvioimaton kirjoitus tieteellisessä lehdessä
Phosphodiester cleavage of diribonucleoside 3 ',3 '-monophosphates: Rate acceleration by the 2 '-hydroxyl and 2 '-amino function, implications to ribozyme action
Tekijät: Ora M, Kiviniemi A, Lonnberg T, Virtanen S, Lonnberg H
Julkaisuvuosi: 2005
Lehti:: Collection Symposium Series
Tietokannassa oleva lehden nimi: Chemistry of Nucleic Acid Components
Lehden akronyymi: COLL SYMPOS SERIES
Vuosikerta: 7
Aloitussivu: 261
Lopetussivu: 263
Sivujen määrä: 3
ISBN: 80-86241-25-4
Tiivistelmä
The hydrolytic reactions of diribonucleoside 3',3'-monophosphates have been followed by RP HPLC over a wide pH-range at 363.2 K. The mechanisms of the reactions are discussed, particularly focusing on the possible stabilization of phosphorane intermediate and/or transition state via an intramolecular hydrogen bonding by the 2'-hydroxyl and 2'-amino group.
The hydrolytic reactions of diribonucleoside 3',3'-monophosphates have been followed by RP HPLC over a wide pH-range at 363.2 K. The mechanisms of the reactions are discussed, particularly focusing on the possible stabilization of phosphorane intermediate and/or transition state via an intramolecular hydrogen bonding by the 2'-hydroxyl and 2'-amino group.
Turun yliopiston Tutkimustietojärjestelmän portaali