Reactions of adenosine with bromo- and chloromalonaldehydes in aqueous solutions: Kinetics and mechanism




Koissi N, Ketomaki K, Neuvonen K, Kuusela S, Lonnberg H

PublisherMARCEL DEKKER INC

1999

Nucleosides & nucleotides

NUCLEOSIDES & NUCLEOTIDES

NUCLEOS NUCLEOT

18

4-5

1095

1096

2

0732-8311

DOIhttps://doi.org/10.1080/15257779908041656(external)



The kinetics of the reactions of adenosine with bromo- and chloromalon-aldehydes to give ethenoadenosine and ethenoformyladenosine has been studied under various conditions. The rate of disappearance of adenosine and the product distribution seen to be dependent on the halogen on the malonaldehyde. Different mechanistic alternatives are discussed, although definite conclusions can not be drawn.



Last updated on 2024-26-11 at 11:51