B1 Non-refereed article in a scientific journal

Reactions of adenosine with bromo- and chloromalonaldehydes in aqueous solutions: Kinetics and mechanism




AuthorsKoissi N, Ketomaki K, Neuvonen K, Kuusela S, Lonnberg H

PublisherMARCEL DEKKER INC

Publication year1999

JournalNucleosides & nucleotides

Journal name in sourceNUCLEOSIDES & NUCLEOTIDES

Journal acronymNUCLEOS NUCLEOT

Volume18

Issue4-5

First page 1095

Last page1096

Number of pages2

ISSN0732-8311

DOIhttps://doi.org/10.1080/15257779908041656


Abstract
The kinetics of the reactions of adenosine with bromo- and chloromalon-aldehydes to give ethenoadenosine and ethenoformyladenosine has been studied under various conditions. The rate of disappearance of adenosine and the product distribution seen to be dependent on the halogen on the malonaldehyde. Different mechanistic alternatives are discussed, although definite conclusions can not be drawn.


Research Areas



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