A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Anti-inflammatory effects of flap and lymph node transfer
Tekijät: Viitanen TP, Visuri MT, Sulo E, Saarikko AM, Hartiala P
Kustantaja: ACADEMIC PRESS INC ELSEVIER SCIENCE
Julkaisuvuosi: 2015
Journal: Journal of Surgical Research
Tietokannassa oleva lehden nimi: JOURNAL OF SURGICAL RESEARCH
Lehden akronyymi: J SURG RES
Vuosikerta: 199
Numero: 2
Aloitussivu: 718
Lopetussivu: 725
Sivujen määrä: 8
ISSN: 0022-4804
DOI: https://doi.org/10.1016/j.jss.2015.04.041
Conclusions: Transfer of healthy tissue hinders the proinflammatory response after surgery, which may explain the beneficial effects of flap transfer in various patient groups. In addition, flap transfer with lymph nodes seems to also promote an antifibrotic effect. The clinical effects of LN in lymphedema patients may be mediated by the increased production of prolymphangiogenic growth factor (VEGF-C) and antifibrotic cytokine (IL-10). (C) 2015 Elsevier Inc. All rights reserved.
