Anti-inflammatory effects of flap and lymph node transfer - UTU Research Portal

A1 Refereed original research article in a scientific journal

Anti-inflammatory effects of flap and lymph node transfer

Authors: Viitanen TP, Visuri MT, Sulo E, Saarikko AM, Hartiala P

Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE

Publication year: 2015

Journal: Journal of Surgical Research

Journal name in source: JOURNAL OF SURGICAL RESEARCH

Journal acronym: J SURG RES

Volume: 199

Issue: 2

First page : 718

Last page: 725

Number of pages: 8

ISSN: 0022-4804

DOI: https://doi.org/10.1016/j.jss.2015.04.041

Abstract

Conclusions: Transfer of healthy tissue hinders the proinflammatory response after surgery, which may explain the beneficial effects of flap transfer in various patient groups. In addition, flap transfer with lymph nodes seems to also promote an antifibrotic effect. The clinical effects of LN in lymphedema patients may be mediated by the increased production of prolymphangiogenic growth factor (VEGF-C) and antifibrotic cytokine (IL-10). (C) 2015 Elsevier Inc. All rights reserved.