68Ga-DOTA-Siglec-9 – a new imaging tool to detect synovitistis




Virtanen H, Autio A, Siitonen R, Liljenback H, Saanijoki T, Lankinen P, Makila J, Kakela M, Teuho J, Savisto N, Jaakkola K, Jalkanen S, Roivainen A

PublisherBIOMED CENTRAL LTD

2015

Arthritis Research and Therapy

ARTHRITIS RESEARCH & THERAPY

ARTHRITIS RES THER

ARTN 308

17

11

1478-6354

DOIhttps://doi.org/10.1186/s13075-015-0826-8

http://arthritis-research.biomedcentral.com/articles/10.1186/s13075-015-0826-8

https://research.utu.fi/converis/portal/detail/Publication/2454038



Conclusion: Ga-DOTA-Siglec-9 PET tracer detected VAP-1 positive vasculature in the mild synovitis of rabbits comparable with F-18-FDG, suggesting its potential for in vivo imaging of synovial inflammation in patients with rheumatic diseases.


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