A polymorphism in the protein kinase C gene PRKCB is associated with alpha(2)-adrenoceptor-mediated vasoconstriction



: Posti JP, Salo P, Ruohonen S, Valve L, Muszkat M, Sofowora GG, Kurnik D, Stein CM, Perola M, Scheinin M, Snapir A

Publisher: LIPPINCOTT WILLIAMS & WILKINS

: 2013

: Pharmacogenetics and Genomics

: PHARMACOGENETICS AND GENOMICS

: PHARMACOGENET GENOM

: 3

: 23

: 3

: 127

: 134

: 8

: 1744-6872

DOI: https://doi.org/10.1097/FPC.0b013e32835d247f


Conclusion Genetic variation in protein kinase C type beta may contribute toward the interindividual variation in DHV constriction responses to alpha(2)-AR activation by the agonist dexmedetomidine. Pharmacogenetics and Genomics 23:127-134 (c) 2013 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.



Last updated on 2024-26-11 at 18:11