Therapeutic potential of thymosin beta 4 in myocardial infarct and heart failure



: Stark C, Taimen P, Tarkia M, Parkka J, Saraste A, Alastalo TP, Savunen T, Koskenvuo J

: 2012

: Annals of the New York Academy of Sciences

: THYMOSINS IN HEALTH AND DISEASE I

: ANN NY ACAD SCI

: 1269

: 117

: 124

: 8

: 0077-8923

DOI: https://doi.org/10.1111/j.1749-6632.2012.06695.x


Thymosin beta 4 (T beta 4) is a peptide known for its abilities to protect and facilitate regeneration in a number of tissues following injury. Its cardioprotective effects have been evaluated in different animal models and, currently, a clinical trial is being planned in patients suffering from acutemyocardial infarction. This paper focuses on the effects of T beta 4 on cardiac function in animal studies utilizing different imaging modalities for outcome measurements.



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