A1 Refereed original research article in a scientific journal
Therapeutic potential of thymosin beta 4 in myocardial infarct and heart failure
Authors: Stark C, Taimen P, Tarkia M, Parkka J, Saraste A, Alastalo TP, Savunen T, Koskenvuo J
Publication year: 2012
Journal: Annals of the New York Academy of Sciences
Journal name in source: THYMOSINS IN HEALTH AND DISEASE I
Journal acronym: ANN NY ACAD SCI
Volume: 1269
First page : 117
Last page: 124
Number of pages: 8
ISSN: 0077-8923
DOI: https://doi.org/10.1111/j.1749-6632.2012.06695.x
Abstract
Thymosin beta 4 (T beta 4) is a peptide known for its abilities to protect and facilitate regeneration in a number of tissues following injury. Its cardioprotective effects have been evaluated in different animal models and, currently, a clinical trial is being planned in patients suffering from acutemyocardial infarction. This paper focuses on the effects of T beta 4 on cardiac function in animal studies utilizing different imaging modalities for outcome measurements.
Thymosin beta 4 (T beta 4) is a peptide known for its abilities to protect and facilitate regeneration in a number of tissues following injury. Its cardioprotective effects have been evaluated in different animal models and, currently, a clinical trial is being planned in patients suffering from acutemyocardial infarction. This paper focuses on the effects of T beta 4 on cardiac function in animal studies utilizing different imaging modalities for outcome measurements.
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