A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Secondary metabolite from Nostoc XPORK14A inhibits photosynthesis and growth of Synechocystis PCC 6803
Tekijät: Sumathy Shunmugam, Jouni Jokela, Matti Wahlsten, Natalia Battchikova, Ateeq ur Rehman, Imre Vass, Maarit Karonen, Jari Sinkkonen, Perttu Permi, Kaarina Sivonen, Eva-Mari Aro, Yagut Allahverdiyeva
Kustantaja: WILEY-BLACKWELL
Julkaisuvuosi: 2014
Journal: Plant, Cell and Environment
Tietokannassa oleva lehden nimi: PLANT CELL AND ENVIRONMENT
Lehden akronyymi: PLANT CELL ENVIRON
Vuosikerta: 37
Numero: 6
Aloitussivu: 1371
Lopetussivu: 1381
Sivujen määrä: 11
ISSN: 0140-7791
DOI: https://doi.org/10.1111/pce.12243
We identified the secondary metabolite of NostocXPORK14A causing these pronounced effects on SynechocystisPCC6803 cells by inhibiting photosynthesis and growth. This compound, designated as M22, has a non-peptide structure. We propose that M22 possesses a dual action mechanism: first, by photo-generation of reactive oxygen species in the presence of light, which in turn affects the photosynthetic machinery of SynechocystisPCC 6803; and second, by altering the in vivo redox status of cells, possibly through inhibition of protein kinases.
