Secondary metabolite from Nostoc XPORK14A inhibits photosynthesis and growth of Synechocystis PCC 6803 - UTU Research Portal

A1 Refereed original research article in a scientific journal

Secondary metabolite from Nostoc XPORK14A inhibits photosynthesis and growth of Synechocystis PCC 6803

Authors: Sumathy Shunmugam, Jouni Jokela, Matti Wahlsten, Natalia Battchikova, Ateeq ur Rehman, Imre Vass, Maarit Karonen, Jari Sinkkonen, Perttu Permi, Kaarina Sivonen, Eva-Mari Aro, Yagut Allahverdiyeva

Publisher: WILEY-BLACKWELL

Publication year: 2014

Journal: Plant, Cell and Environment

Journal name in source: PLANT CELL AND ENVIRONMENT

Journal acronym: PLANT CELL ENVIRON

Volume: 37

Issue: 6

First page : 1371

Last page: 1381

Number of pages: 11

ISSN: 0140-7791

DOI: https://doi.org/10.1111/pce.12243

Abstract

We identified the secondary metabolite of NostocXPORK14A causing these pronounced effects on SynechocystisPCC6803 cells by inhibiting photosynthesis and growth. This compound, designated as M22, has a non-peptide structure. We propose that M22 possesses a dual action mechanism: first, by photo-generation of reactive oxygen species in the presence of light, which in turn affects the photosynthetic machinery of SynechocystisPCC 6803; and second, by altering the in vivo redox status of cells, possibly through inhibition of protein kinases.