A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
High Intestinal Cholesterol Absorption Is Associated With Cardiovascular Disease and Risk Alleles in ABCG8 and ABO Evidence From the LURIC and YFS Cohorts and From a Meta-Analysis
Tekijät: Silbernagel G, Chapman MJ, Genser B, Kleber ME, Fauler G, Scharnagl H, Grammer TB, Boehm BO, Makela KM, Kahonen M, Carmena R, Rietzschel ER, Bruckert E, Deanfield JE, Miettinen TA, Raitakari OT, Lehtimaki T, Marz W
Kustantaja: ELSEVIER SCIENCE INC
Julkaisuvuosi: 2013
Journal: Journal of the American College of Cardiology
Tietokannassa oleva lehden nimi: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Lehden akronyymi: J AM COLL CARDIOL
Numero sarjassa: 4
Vuosikerta: 62
Numero: 4
Aloitussivu: 291
Lopetussivu: 299
Sivujen määrä: 9
ISSN: 0735-1097
DOI: https://doi.org/10.1016/j.jacc.2013.01.100
Conclusions High cholesterol absorption is associated with risk alleles in ABCG8 and ABO and with CVD. Harm caused by elevated cholesterol absorption rather than by plant sterols may therefore mediate the relationships of ABCG8 and ABO variants with CVD. (C) 2013 by the American College of Cardiology Foundation
