Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events AtheroRemo Consortium
: Makela KM, Seppala I, Hernesniemi JA, Lyytikainen LP, Oksala N, Kleber ME, Scharnagl H, Grammer TB, Baumert J, Thorand B, Jula A, Hutri-Kahonen N, Juonala M, Laitinen T, Laaksonen R, Karhunen PJ, Nikus KC, Nieminen T, Laurikka J, Kuukasjarvi P, Tarkka M, Viik J, Klopp N, Illig T, Kettunen J, Ahotupa M, Viikari JSA, Kahonen M, Raitakari OT, Karakas M, Koenig W, Boehm BO, Winkelmann BR, Marz W, Lehtimaki T
Publisher: LIPPINCOTT WILLIAMS & WILKINS
: 2013
: Circulation: Cardiovascular Genetics
: CIRCULATION-CARDIOVASCULAR GENETICS
: CIRC-CARDIOVASC GENE
: 1
: 6
: 1
: 73
: 81
: 9
: 1942-325X
DOI: https://doi.org/10.1161/CIRCGENETICS.112.964965(external)
Conclusions-This novel genetic marker is an important factor regulating oxidized low-density lipoprotein levels but not a major genetic factor for the studied cardiovascular endpoints. (Circ Cardiovasc Genet. 2013;6:73-81.)