Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events AtheroRemo Consortium




Makela KM, Seppala I, Hernesniemi JA, Lyytikainen LP, Oksala N, Kleber ME, Scharnagl H, Grammer TB, Baumert J, Thorand B, Jula A, Hutri-Kahonen N, Juonala M, Laitinen T, Laaksonen R, Karhunen PJ, Nikus KC, Nieminen T, Laurikka J, Kuukasjarvi P, Tarkka M, Viik J, Klopp N, Illig T, Kettunen J, Ahotupa M, Viikari JSA, Kahonen M, Raitakari OT, Karakas M, Koenig W, Boehm BO, Winkelmann BR, Marz W, Lehtimaki T

PublisherLIPPINCOTT WILLIAMS & WILKINS

2013

Circulation: Cardiovascular Genetics

CIRCULATION-CARDIOVASCULAR GENETICS

CIRC-CARDIOVASC GENE

1

6

1

73

81

9

1942-325X

DOIhttps://doi.org/10.1161/CIRCGENETICS.112.964965(external)



Conclusions-This novel genetic marker is an important factor regulating oxidized low-density lipoprotein levels but not a major genetic factor for the studied cardiovascular endpoints. (Circ Cardiovasc Genet. 2013;6:73-81.)



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