Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events AtheroRemo Consortium - UTU Research Portal

A1 Refereed original research article in a scientific journal

Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events AtheroRemo Consortium

Authors: Makela KM, Seppala I, Hernesniemi JA, Lyytikainen LP, Oksala N, Kleber ME, Scharnagl H, Grammer TB, Baumert J, Thorand B, Jula A, Hutri-Kahonen N, Juonala M, Laitinen T, Laaksonen R, Karhunen PJ, Nikus KC, Nieminen T, Laurikka J, Kuukasjarvi P, Tarkka M, Viik J, Klopp N, Illig T, Kettunen J, Ahotupa M, Viikari JSA, Kahonen M, Raitakari OT, Karakas M, Koenig W, Boehm BO, Winkelmann BR, Marz W, Lehtimaki T

Publisher: LIPPINCOTT WILLIAMS & WILKINS

Publication year: 2013

Journal: Circulation: Cardiovascular Genetics

Journal name in source: CIRCULATION-CARDIOVASCULAR GENETICS

Journal acronym: CIRC-CARDIOVASC GENE

Number in series: 1

Volume: 6

Issue: 1

First page : 73

Last page: 81

Number of pages: 9

ISSN: 1942-325X

DOI: https://doi.org/10.1161/CIRCGENETICS.112.964965(external)

Abstract

Conclusions-This novel genetic marker is an important factor regulating oxidized low-density lipoprotein levels but not a major genetic factor for the studied cardiovascular endpoints. (Circ Cardiovasc Genet. 2013;6:73-81.)