A1 Refereed original research article in a scientific journal
The Spectrum of Genital Human Papillomavirus Infection Among Men Attending a Swedish Sexually-transmitted Infections Clinic: Human Papillomavirus Typing and Clinical Presentation of Histopathologically Benign Lesions
Authors: Wikstrom A, Vassilaki I, Hedblad MA, Syrjanen S
Publisher: ACTA DERMATO-VENEREOLOGICA
Publication year: 2013
Journal: Acta Dermato-Venereologica
Journal name in source: ACTA DERMATO-VENEREOLOGICA
Journal acronym: ACTA DERM-VENEREOL
Number in series: 2
Volume: 93
Issue: 2
First page : 223
Last page: 227
Number of pages: 5
ISSN: 0001-5555
DOI: https://doi.org/10.2340/00015555-1375
Abstract
There have been a number of Swedish studies on human papillomavirus (HPV) typing in men, most of which have used less sensitive HPV-typing techniques. The present study included male patients with genital HPV-induced lesions planned for surgery. Samples were prepared for histopathology and PCR. HPV was detected in 233/253 (92%) and HPV 6 or 11 in 89% of the HPV-positive lesions. There were statistically significant differences regarding morphology (p=0.002), location (p=0.000001) and colour (p=0.005) of the lesions for low- vs. mixed or high-risk HPV types. For example, acuminate lesions were mostly found among men with low-risk HPV types, whereas macular lesions were over-represented among them with mixed or high-risk types. The HPV type distribution is similar to that in earlier studies, but we also found correlations with some clinical parameters.
There have been a number of Swedish studies on human papillomavirus (HPV) typing in men, most of which have used less sensitive HPV-typing techniques. The present study included male patients with genital HPV-induced lesions planned for surgery. Samples were prepared for histopathology and PCR. HPV was detected in 233/253 (92%) and HPV 6 or 11 in 89% of the HPV-positive lesions. There were statistically significant differences regarding morphology (p=0.002), location (p=0.000001) and colour (p=0.005) of the lesions for low- vs. mixed or high-risk HPV types. For example, acuminate lesions were mostly found among men with low-risk HPV types, whereas macular lesions were over-represented among them with mixed or high-risk types. The HPV type distribution is similar to that in earlier studies, but we also found correlations with some clinical parameters.
UTU Research Portal