Patient-derived tissue culture and xenograft models for studying prostate tumor responses to therapy
: Yu L, Kahkonen TE, Taimen P, Bostrom P, Tuomela J, Harkonen P
Publisher: ELSEVIER SCI LTD
: 2014
: European Journal of Cancer
: EUROPEAN JOURNAL OF CANCER
: EUR J CANCER
: 50
: suppl. 5
: S52
: S52
: 1
: 0959-8049
DOI: https://doi.org/10.1016/S0959-8049(14)50196-7
Conclusion: According to our preliminary results, patient-derived xenografts
and tissue cultures maintain viability and appropriate responses to androgen.
Furthermore, PDX models may be useful for testing the individual responses
of prostate cancer patients to therapeutics, which would allow developing a
tool for personalized medicine to be used in prostate cancer research.