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Patient-derived tissue culture and xenograft models for studying prostate tumor responses to therapy



Authors: Yu L, Kahkonen TE, Taimen P, Bostrom P, Tuomela J, Harkonen P

Publisher: ELSEVIER SCI LTD

Publication year: 2014

Journal: European Journal of Cancer

Journal name in source: EUROPEAN JOURNAL OF CANCER

Journal acronym: EUR J CANCER

Volume: 50

Issue: suppl. 5

First page : S52

Last page: S52

Number of pages: 1

ISSN: 0959-8049

DOI: https://doi.org/10.1016/S0959-8049(14)50196-7


Abstract

Conclusion: According to our preliminary results, patient-derived xenografts

and tissue cultures maintain viability and appropriate responses to androgen.

Furthermore, PDX models may be useful for testing the individual responses

of prostate cancer patients to therapeutics, which would allow developing a

tool for personalized medicine to be used in prostate cancer research.




Last updated on 2024-26-11 at 12:19