Dietary counseling and probiotic supplementation during pregnancy modify placental phospholipid fatty acids

: Kaplas N, Isolauri E, Lampi AM, Ojala T, Laitinen K

Publisher: SPRINGER

: 2007

Lipids

: LIPIDS

: 42

: 9

: 865

: 870

: 6

: 0024-4201

DOI: https://doi.org/10.1007/s11745-007-3094-9

It has previously been shown that maternal nutrition affects the fetal environment, with consequences for the infant's health. From early pregnancy onwards participants here received a combination of dietary counseling and probiotics (Lactobacillus GG and Bifidobacterium lactis Bb12; n = 10), dietary counseling with placebo (n = 12), or placebo alone (n = 8). The major differences in placental fatty acids were attributable to a higher concentration of n-3 polyunsaturated fatty acids in both intervention arms than in controls. Further, dietary counseling with probiotics resulted in higher concentrations of linoleic (18:2n-6) and dihomo-gamma-linolenic acids (20:3n-6) compared with dietary counseling with placebo or controls.