A1 Refereed original research article in a scientific journal
Dietary counseling and probiotic supplementation during pregnancy modify placental phospholipid fatty acids
Authors: Kaplas N, Isolauri E, Lampi AM, Ojala T, Laitinen K
Publisher: SPRINGER
Publication year: 2007
Journal: Lipids
Journal name in source: LIPIDS
Journal acronym: LIPIDS
Volume: 42
Issue: 9
First page : 865
Last page: 870
Number of pages: 6
ISSN: 0024-4201
DOI: https://doi.org/10.1007/s11745-007-3094-9
Abstract
It has previously been shown that maternal nutrition affects the fetal environment, with consequences for the infant's health. From early pregnancy onwards participants here received a combination of dietary counseling and probiotics (Lactobacillus GG and Bifidobacterium lactis Bb12; n = 10), dietary counseling with placebo (n = 12), or placebo alone (n = 8). The major differences in placental fatty acids were attributable to a higher concentration of n-3 polyunsaturated fatty acids in both intervention arms than in controls. Further, dietary counseling with probiotics resulted in higher concentrations of linoleic (18:2n-6) and dihomo-gamma-linolenic acids (20:3n-6) compared with dietary counseling with placebo or controls.
It has previously been shown that maternal nutrition affects the fetal environment, with consequences for the infant's health. From early pregnancy onwards participants here received a combination of dietary counseling and probiotics (Lactobacillus GG and Bifidobacterium lactis Bb12; n = 10), dietary counseling with placebo (n = 12), or placebo alone (n = 8). The major differences in placental fatty acids were attributable to a higher concentration of n-3 polyunsaturated fatty acids in both intervention arms than in controls. Further, dietary counseling with probiotics resulted in higher concentrations of linoleic (18:2n-6) and dihomo-gamma-linolenic acids (20:3n-6) compared with dietary counseling with placebo or controls.