Refereed journal article or data article (A1)
Epimers vs. inverse epimers: the C-1 configuration in alnumycin A1
List of Authors: Tahtinen P, Oja T, Dreiack N, Mantsala P, Niemi J, Metsa-Ketela M, Klika KD
Publisher: ROYAL SOC CHEMISTRY
Publication year: 2012
Journal: RSC Advances
Journal name in source: RSC ADVANCES
Journal acronym: RSC ADV
Number in series: 12
Volume number: 2
Issue number: 12
Number of pages: 3
ISSN: 2046-2069
DOI: http://dx.doi.org/10.1039/c2ra20537h
Abstract
The determination of whether two stereoisomers constitute an epimeric pair or if they differ in their configuration at all stereogenic centers bar one can be deceptive, and even more problematic than just absolute configuration determination per se. The latter stereochemical relationship is hereby defined as a pair of inverse epimers and is exemplified by alnumycin A1 to introduce the concept.
The determination of whether two stereoisomers constitute an epimeric pair or if they differ in their configuration at all stereogenic centers bar one can be deceptive, and even more problematic than just absolute configuration determination per se. The latter stereochemical relationship is hereby defined as a pair of inverse epimers and is exemplified by alnumycin A1 to introduce the concept.
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