Refereed journal article or data article (A1)

Environmental stimuli shape biofilm formation and the virulence of periodontal pathogens

List of AuthorsPöllänen M T, Paino A, Ihalin R

Publication year2013

JournalInternational Journal of Molecular Sciences

Journal name in sourceInternational Journal of Molecular Sciences

Number in series8

Volume number14

Issue number8

Start page17221

End page17237

Number of pages17



Periodontitis is a common inflammatory disease affecting the tooth-supporting structures. It is initiated by bacteria growing as a biofilm at the gingival margin, and communication of the biofilms differs in health and disease. The bacterial composition of periodontitis-associated biofilms has been well documented and is under continual investigation. However, the roles of several host response and inflammation driven environmental stimuli on biofilm formation is not well understood. This review article addresses the effects of environmental factors such as pH, temperature, cytokines, hormones, and oxidative stress on periodontal biofilm formation and bacterial virulence. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

Last updated on 2021-24-06 at 09:20