A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Environmental stimuli shape biofilm formation and the virulence of periodontal pathogens
Tekijät: Pöllänen M T, Paino A, Ihalin R
Julkaisuvuosi: 2013
Journal: International Journal of Molecular Sciences
Tietokannassa oleva lehden nimi: International Journal of Molecular Sciences
Numero sarjassa: 8
Vuosikerta: 14
Numero: 8
Aloitussivu: 17221
Lopetussivu: 17237
Sivujen määrä: 17
ISSN: 1422-0067
DOI: https://doi.org/10.3390/ijms140817221
Tiivistelmä
Periodontitis is a common inflammatory disease affecting the tooth-supporting structures. It is initiated by bacteria growing as a biofilm at the gingival margin, and communication of the biofilms differs in health and disease. The bacterial composition of periodontitis-associated biofilms has been well documented and is under continual investigation. However, the roles of several host response and inflammation driven environmental stimuli on biofilm formation is not well understood. This review article addresses the effects of environmental factors such as pH, temperature, cytokines, hormones, and oxidative stress on periodontal biofilm formation and bacterial virulence. © 2013 by the authors; licensee MDPI, Basel, Switzerland.
Periodontitis is a common inflammatory disease affecting the tooth-supporting structures. It is initiated by bacteria growing as a biofilm at the gingival margin, and communication of the biofilms differs in health and disease. The bacterial composition of periodontitis-associated biofilms has been well documented and is under continual investigation. However, the roles of several host response and inflammation driven environmental stimuli on biofilm formation is not well understood. This review article addresses the effects of environmental factors such as pH, temperature, cytokines, hormones, and oxidative stress on periodontal biofilm formation and bacterial virulence. © 2013 by the authors; licensee MDPI, Basel, Switzerland.
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