A1 Refereed original research article in a scientific journal

Generation of three isogenic human induced pluripotent stem cell lines from normal neonate skin fibroblasts




AuthorsSandelin Sanne, Hakala Sofia, Lehtinen Laura, Närvä Elisa

Publication year2024

JournalStem Cell Research

Journal name in sourceStem cell research

Journal acronymStem Cell Res

Article number103301

Volume74

ISSN1873-5061

eISSN1876-7753

DOIhttps://doi.org/10.1016/j.scr.2023.103301

Web address https://doi.org/10.1016/j.scr.2023.103301

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/193202455


Abstract
Characterized human induced pluripotent stem cell lines are important for basic research. Here, we report the establishment of three isogenic human induced pluripotent stem cell (hiPSC) lines generated from normal neonate male skin fibroblasts. Pluripotency was induced using the integration free Sendai virus reprogramming method. The pluripotency, identity, quality, and safety of the lines were confirmed to establish characterized human induced pluripotent stem cell lines to be used as normal control cell lines in future studies.

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Last updated on 2024-26-11 at 22:55