A1 Refereed original research article in a scientific journal
Cleavage and isomerisation of UpU promoted by dinuclear metal ion complexes
Authors: Linjalahti H, Feng G, Mareque-Rivas JC, Mikkola S, Williams NH
Publication year: 2008
Journal name in source: CHEMISTRY OF NUCLEIC ACID COMPONENTS
Journal acronym: COLL SYMPOS SERIES
Volume: 10
First page : 404
Last page: 406
Number of pages: 3
ISBN: 978-80-86241-29-6
Abstract
Reactions of UpU with dinuclear metal ion complexes have been studied. The complexes did not only efficiently promote the cleavage of the phosphodiester bond but, remarkably, catalysed the isomerisation of the diester. This implies that the reaction involves the formation of a sufficiently long-lived phosphorane intermediate which can pseudorotate.
Reactions of UpU with dinuclear metal ion complexes have been studied. The complexes did not only efficiently promote the cleavage of the phosphodiester bond but, remarkably, catalysed the isomerisation of the diester. This implies that the reaction involves the formation of a sufficiently long-lived phosphorane intermediate which can pseudorotate.
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