Directed antibody-engineering techniques and their applications in food immunoassays

: Markus V, Janne L, Urpo L

Publisher: ELSEVIER SCI LTD

: 2011

: Trends in Analytical Chemistry

: TRAC-TRENDS IN ANALYTICAL CHEMISTRY

: TRAC-TREND ANAL CHEM

: 2

: 30

: 2

: 219

: 226

: 8

: 0165-9936

DOI: https://doi.org/10.1016/j.trac.2011.01.001

The use of antibodies in immunodiagnostics has achieved new insights with recombinant technologies. This review summarizes the methods used to produce recombinant antibodies and those to tailor their properties. Finally, we address the advantages and the possibilities of recombinant antibodies in immunoanalytical applications through examples with the main focus on applications related to food quality and safety analysis. (C) 2011 Elsevier Ltd. All rights reserved.