A1 Refereed original research article in a scientific journal
Directed antibody-engineering techniques and their applications in food immunoassays
Authors: Markus V, Janne L, Urpo L
Publisher: ELSEVIER SCI LTD
Publication year: 2011
Journal: Trends in Analytical Chemistry
Journal name in source: TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Journal acronym: TRAC-TREND ANAL CHEM
Number in series: 2
Volume: 30
Issue: 2
First page : 219
Last page: 226
Number of pages: 8
ISSN: 0165-9936
DOI: https://doi.org/10.1016/j.trac.2011.01.001
Abstract
The use of antibodies in immunodiagnostics has achieved new insights with recombinant technologies. This review summarizes the methods used to produce recombinant antibodies and those to tailor their properties. Finally, we address the advantages and the possibilities of recombinant antibodies in immunoanalytical applications through examples with the main focus on applications related to food quality and safety analysis. (C) 2011 Elsevier Ltd. All rights reserved.
The use of antibodies in immunodiagnostics has achieved new insights with recombinant technologies. This review summarizes the methods used to produce recombinant antibodies and those to tailor their properties. Finally, we address the advantages and the possibilities of recombinant antibodies in immunoanalytical applications through examples with the main focus on applications related to food quality and safety analysis. (C) 2011 Elsevier Ltd. All rights reserved.