A1 Refereed original research article in a scientific journal

Directed antibody-engineering techniques and their applications in food immunoassays




AuthorsMarkus V, Janne L, Urpo L

PublisherELSEVIER SCI LTD

Publication year2011

JournalTrends in Analytical Chemistry

Journal name in sourceTRAC-TRENDS IN ANALYTICAL CHEMISTRY

Journal acronymTRAC-TREND ANAL CHEM

Number in series2

Volume30

Issue2

First page 219

Last page226

Number of pages8

ISSN0165-9936

DOIhttps://doi.org/10.1016/j.trac.2011.01.001


Abstract
The use of antibodies in immunodiagnostics has achieved new insights with recombinant technologies. This review summarizes the methods used to produce recombinant antibodies and those to tailor their properties. Finally, we address the advantages and the possibilities of recombinant antibodies in immunoanalytical applications through examples with the main focus on applications related to food quality and safety analysis. (C) 2011 Elsevier Ltd. All rights reserved.



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