A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
The emergence of genotypes 3 and 4 hepatitis E virus in swine and humans: a phylogenetic perspective
Tekijät: Xia HY, Wahlberg N, Belak S, Meng XJ, Liu LH
Kustantaja: SPRINGER WIEN
Julkaisuvuosi: 2011
Journal: Archives of Virology
Tietokannassa oleva lehden nimi: ARCHIVES OF VIROLOGY
Lehden akronyymi: ARCH VIROL
Numero sarjassa: 1
Vuosikerta: 156
Numero: 1
Aloitussivu: 121
Lopetussivu: 124
Sivujen määrä: 4
ISSN: 0304-8608
DOI: https://doi.org/10.1007/s00705-010-0818-6
Tiivistelmä
To investigate whether there is any phylogenetic evidence to support the hypothesis that swine is the natural host of HEV genotypes 3 and 4, Bayesian analysis of 80 full-length genomic sequences of HEV was performed. The results showed that the strains of genotypes 3 and 4 from swine are paraphyletic with regard to strains of human origin, which are thus phylogenetically nested among the swine strains. Recognition of HEV genotypes 3 and 4 as viruses from swine or swine HEV can provide an evolutionary explanation to the observation of cross-species infection by genotypes 3 and 4 HEV.
To investigate whether there is any phylogenetic evidence to support the hypothesis that swine is the natural host of HEV genotypes 3 and 4, Bayesian analysis of 80 full-length genomic sequences of HEV was performed. The results showed that the strains of genotypes 3 and 4 from swine are paraphyletic with regard to strains of human origin, which are thus phylogenetically nested among the swine strains. Recognition of HEV genotypes 3 and 4 as viruses from swine or swine HEV can provide an evolutionary explanation to the observation of cross-species infection by genotypes 3 and 4 HEV.
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