A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Effects of Cannabinor, a Novel Selective Cannabinoid 2 Receptor Agonist, on Bladder Function in Normal Rats
Tekijät: Gratzke C, Streng T, Stief CG, Downs TR, Alroy I, Rosenbaum JS, Andersson KE, Hedlund P
Kustantaja: ELSEVIER SCIENCE BV
Julkaisuvuosi: 2010
Journal: European Urology
Tietokannassa oleva lehden nimi: EUROPEAN UROLOGY
Lehden akronyymi: EUR UROL
Numero sarjassa: 6
Vuosikerta: 57
Numero: 6
Aloitussivu: 1093
Lopetussivu: 1100
Sivujen määrä: 8
ISSN: 0302-2838
DOI: https://doi.org/10.1016/j.eururo.2010.02.027
Tiivistelmä
Conclusions: Considering that CB2 receptors are localized on sensory nerves and on the urothelium and that cannabinor had effects on "afferent'' urodynamic parameters, peripheral CB2 receptors may be involved in sensory functions of rat micturition. Effects of cannabinor on cholinergic nerve activity in normal bladder tissue appear to be limited. (c) 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved.
Conclusions: Considering that CB2 receptors are localized on sensory nerves and on the urothelium and that cannabinor had effects on "afferent'' urodynamic parameters, peripheral CB2 receptors may be involved in sensory functions of rat micturition. Effects of cannabinor on cholinergic nerve activity in normal bladder tissue appear to be limited. (c) 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved.
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