A1 Refereed original research article in a scientific journal
Effects of Cannabinor, a Novel Selective Cannabinoid 2 Receptor Agonist, on Bladder Function in Normal Rats
Authors: Gratzke C, Streng T, Stief CG, Downs TR, Alroy I, Rosenbaum JS, Andersson KE, Hedlund P
Publisher: ELSEVIER SCIENCE BV
Publication year: 2010
Journal: European Urology
Journal name in source: EUROPEAN UROLOGY
Journal acronym: EUR UROL
Number in series: 6
Volume: 57
Issue: 6
First page : 1093
Last page: 1100
Number of pages: 8
ISSN: 0302-2838
DOI: https://doi.org/10.1016/j.eururo.2010.02.027(external)
Abstract
Conclusions: Considering that CB2 receptors are localized on sensory nerves and on the urothelium and that cannabinor had effects on "afferent'' urodynamic parameters, peripheral CB2 receptors may be involved in sensory functions of rat micturition. Effects of cannabinor on cholinergic nerve activity in normal bladder tissue appear to be limited. (c) 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved.
Conclusions: Considering that CB2 receptors are localized on sensory nerves and on the urothelium and that cannabinor had effects on "afferent'' urodynamic parameters, peripheral CB2 receptors may be involved in sensory functions of rat micturition. Effects of cannabinor on cholinergic nerve activity in normal bladder tissue appear to be limited. (c) 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved.
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