CXCL13 and neopterin concentrations in cerebrospinal fluid of patients with Lyme neuroborreliosis and other diseases that cause neuroinflammation

: Hytonen J, Kortela E, Waris M, Puustinen J, Salo J, Oksi J

Publisher: BIOMED CENTRAL LTD

: 2014

: Journal of Neuroinflammation

: JOURNAL OF NEUROINFLAMMATION

: J NEUROINFLAMM

: ARTN 103

: 11

: 1742-2094

DOI: https://doi.org/10.1186/1742-2094-11-103

Conclusions: These results clearly indicate that highly elevated CSF CXCL13 levels are strongly associated with untreated LNB. CXCL13 outperformed neopterin and appears to be an excellent biomarker in differentiating LNB from viral CNS infections and from other neuroinflammatory conditions.