A1 Refereed original research article in a scientific journal
CXCL13 and neopterin concentrations in cerebrospinal fluid of patients with Lyme neuroborreliosis and other diseases that cause neuroinflammation
Authors: Hytonen J, Kortela E, Waris M, Puustinen J, Salo J, Oksi J
Publisher: BIOMED CENTRAL LTD
Publication year: 2014
Journal: Journal of Neuroinflammation
Journal name in source: JOURNAL OF NEUROINFLAMMATION
Journal acronym: J NEUROINFLAMM
Article number: ARTN 103
Volume: 11
Number of pages: 11
ISSN: 1742-2094
DOI: https://doi.org/10.1186/1742-2094-11-103
Conclusions: These results clearly indicate that highly elevated CSF CXCL13 levels are strongly associated with untreated LNB. CXCL13 outperformed neopterin and appears to be an excellent biomarker in differentiating LNB from viral CNS infections and from other neuroinflammatory conditions.