Development and clinical validation of a miniaturized finger probe for bedside hemodynamic monitoring

: Panula Tuukka, Sirkiä Jukka-Pekka, Koivisto Tero, Pänkäälä Mikko, Niiranen Teemu, Kantola Ilkka, Kaisti Matti

Publisher: Cell Press

: 2023

: iScience

: 108295

: 26

: 11

: 2589-0042

DOI: https://doi.org/10.1016/j.isci.2023.108295(external)

: https://doi.org/10.1016/j.isci.2023.108295(external)

: https://research.utu.fi/converis/portal/detail/Publication/181784765(external)

Our aim is to develop a blood pressure (BP) measurement technology that could be integrated into a finger-worn pulse oximeter, eliminating the need for a brachial cuff. We present a miniature cuffless tonometric finger probe system that uses the oscillometric method to measure BP. Our approach uses a motorized press that is used to apply pressure to the fingertip to measure BP. We verified the functionality of the device in a clinical trial (n = 43) resulting in systolic and diastolic pressures ((mean ± SD) mmHg) of (-3.5 ± 8.4) mmHg and (-4.0 ± 4.4) mmHg, respectively. Comparison was made with manual auscultation (n = 26) and automated cuff oscillometry (n = 18). In addition to BP, we demonstrated the ability of the device to assess arterial stiffness (n = 18) and detect atrial fibrillation (n = 6). We were able to introduce a sufficiently small device that could be used for convenient ambulatory measurements with minimal discomfort.

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