A1 Refereed original research article in a scientific journal

Practice patterns in diagnostics, staging, and management strategies of gallbladder cancer among Nordic tertiary centers




AuthorsTakala Sini, Lassen Kristoffer, Soreide Kjetil, Sparrelid Ernesto, Angelsen Jon-Helge, Bringeland Erling A., Eilard Malin S., Hemmingsson Oskar, Isaksson Bengt, Karjula Heikki, Lammi Jukka-Pekka, Larsen Peter N., Lavonius Maija, Lindell Gert, Mortensen Frank V., Mortensen Kim, Nordin Arno, Pless Torsten, Sandström Per, Sandvik Oddvar, Vaalavuo Yrjö, Villard Christina, Sallinen Ville

PublisherSAGE PUBLICATIONS LTD

Publication year2023

JournalScandinavian Journal of Surgery

Journal name in sourceSCANDINAVIAN JOURNAL OF SURGERY

Journal acronymSCAND J SURG

Volume112

First page 147

Last page156

Number of pages10

ISSN1457-4969

eISSN1799-7267

DOIhttps://doi.org/10.1177/14574969231181228

Web address https://doi.org/10.1177/14574969231181228

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/180789680


Abstract

Background and objective: Gallbladder cancer (GBC) is a rare malignancy in the Nordic countries and no common Nordic treatment guidelines exist. This study aimed to characterize the current diagnostic and treatment strategies in the Nordic countries and disclose differences in these strategies.

Methods: This was a survey study with a cross-sectional questionnaire of all 19 university hospitals providing curative-intent surgery for GBC in Sweden, Norway, Denmark, and Finland.

Results: In all Nordic countries except Sweden, neoadjuvant/downstaging chemotherapy was used in GBC patients. In T1b and T2, majority of the centers (15-18/19) performed extended cholecystectomy. In T3, majority of the centers (13/19) performed cholecystectomy with resection of segments 4b and 5. In T4, majority of the centers (12-14/19) chose palliative/oncological care. The centers in Sweden extended lymphadenectomy beyond the hepatoduodenal ligament, whereas all other Nordic centers usually limited lymphadenectomy to the hepatoduodenal ligament. All Nordic centers except those in Norway used adjuvant chemotherapy routinely for GBC. There were no major differences between the Nordic centers in diagnostics and follow-up.

Conclusions: The surgical and oncological treatment strategies of GBC vary considerably between the Nordic centers and countries.


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Last updated on 2024-26-11 at 19:57