A1 Refereed original research article in a scientific journal
Childhood family environment predicting psychotic disorders over a 37-year follow-up-A general population cohort study
Authors: Saarinen Aino, Keltikangas-Jarvinen Liisa, Dobewall Henrik, Sormunen Elina, Lehtimäki Terho, Kähönen Mika, Raitakari Olli, Hietala Jarmo
Publisher: ELSEVIER
Publication year: 2023
Journal: Schizophrenia Research
Journal name in source: SCHIZOPHRENIA RESEARCH
Journal acronym: SCHIZOPHR RES
Volume: 258
First page : 9
Last page: 17
Number of pages: 9
ISSN: 0920-9964
DOI: https://doi.org/10.1016/j.schres.2023.06.008
Web address : https://doi.org/10.1016/j.schres.2023.06.008
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/180579758
Background: Childhood adverse effects and traumatic experiences increase the risk for several psychiatric disorders. We now investigated whether prospectively assessed childhood family environment per se contributes to increased risk for psychotic disorders in adulthood, and whether these family patterns are also relevant in the development of affective disorders.
Methods: We used the Young Finns Data (n = 3502). Childhood family environment was assessed in 1980/1983 with previously constructed risk scores: (1) disadvantageous emotional family atmosphere (parenting practices, parents' life satisfaction, parents' mental disorder, parents' alcohol intoxication), (2) adverse socioeconomic environment (overcrowded apartment, home income, parent's employment, occupational status, educational level), and (3) stress-prone life events (home movement, school change, parental divorce, death, or hospitalization, and child's hospitalization). Psychiatric diagnoses (ICD-10 classification) over the lifespan were collected up to 2017 from the national registry of hospital care. Non-affective psychotic disorder and affective disorder groups were formed.
Results: Frequent stress-prone life events predicted higher likelihood of non-affective psychotic disorders (OR = 2.401, p = 0.001). Adverse socioeconomic environment or emotional family atmosphere did not predict psychotic disorders. Only disadvantageous emotional family atmosphere predicted modestly higher likelihood of affective disorders (OR = 1.583, p = 0.013).
Conclusions: Our results suggest that childhood family environment and atmosphere patterns as such contribute to the risk for developing adulthood mental disorders with relative disorder specificity. The results emphasize the importance of both individual and public health preventive initiatives, including family support interventions.
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