A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Human Milk Microbiota Profile Affected by Prematurity in Argentinian Lactating Women
Tekijät: Oddi Sofia, Mantziari Anastasia, Huber Paula, Binetti Ana, Salminen Seppo, Collado Maria Carmen, Vinderola Gabriel
Kustantaja: MDPI
Julkaisuvuosi: 2023
Journal: Microorganisms
Tietokannassa oleva lehden nimi: MICROORGANISMS
Lehden akronyymi: MICROORGANISMS
Artikkelin numero: 1090
Vuosikerta: 11
Numero: 4
Sivujen määrä: 14
DOI: https://doi.org/10.3390/microorganisms11041090
Verkko-osoite: https://www.mdpi.com/2076-2607/11/4/1090
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/179712083
To study (16S rRNA-sequencing) the impact of gestational and corrected ages on the microbiota profile of human milk (HM) of mothers that delivered full-term and pre-term children, HM samples were obtained and classified according to the gestational age as group T (full-term births >= 37 weeks), and group P (pre-term births <37 weeks). Group P was longitudinally followed, and the samples were collected at the full-term corrected gestational age: when the chronological age plus the gestational age were >= 37 weeks (PT group). The HM microbiota composition differed depending on the gestational age (T vs. P). Group T had lower levels of Staphylococcus and higher levels of Rothia and Streptococcus, as compared to group P. The alpha Simpson diversity value was higher in group T than in P, whereas no differences were found between groups T and PT, suggesting a microbial evolution of the composition of group P towards group T over chronological age. Full-term delivery was associated with a greater diversity of microbes in HM. The microbial composition of pre-term HM, at the corrected age, did not show significant differences, as compared to the samples obtained from the full-term group, suggesting that it would be appropriate to consider the corrected age in terms of the composition and the diversity of the milk in future studies.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
