A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä

Electronic health records to facilitate clinical research




TekijätCowie MR, Blomster JI, Curtis LH4, Duclaux S, Ford I, Fritz F, Goldman S, Janmohamed S, Kreuzer J, Leenay M, Michel A, Ong S, Pell JP, Southworth MR, Stough WG, Thoenes M, Zannad F, Zalewski A

KustantajaSPRINGER

Julkaisuvuosi2017

JournalClinical Research in Cardiology

Vuosikerta106

Numero1

Aloitussivu1

Lopetussivu9

Sivujen määrä9

ISSN1861-0684

DOIhttps://doi.org/10.1007/s00392-016-1025-6

Verkko-osoitehttps://link.springer.com/article/10.1007/s00392-016-1025-6

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/17962385


Tiivistelmä

Electronic health records (EHRs) provide opportunities to enhance patient care, embed performance measures in clinical practice, and facilitate clinical research. Concerns have been raised about the increasing recruitment challenges in trials, burdensome and obtrusive data collection, and uncertain generalizability of the results. Leveraging electronic health records to counterbalance these trends is an area of intense interest. The initial applications of electronic health records, as the primary data source is envisioned for observational studies, embedded pragmatic or post-marketing registry-based randomized studies, or comparative effectiveness studies. Advancing this approach to randomized clinical trials, electronic health records may potentially be used to assess study feasibility, to facilitate patient recruitment, and streamline data collection at baseline and follow-up. Ensuring data security and privacy, overcoming the challenges associated with linking diverse systems and maintaining infrastructure for repeat use of high quality data, are some of the challenges associated with using electronic health records in clinical research. Collaboration between academia, industry, regulatory bodies, policy makers, patients, and electronic health record vendors is critical for the greater use of electronic health records in clinical research. This manuscript identifies the key steps required to advance the role of electronic health records in cardiovascular clinical research.


Ladattava julkaisu

This is an electronic reprint of the original article.
This reprint may differ from the original in pagination and typographic detail. Please cite the original version.





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