Refereed review article in scientific journal (A2)

Burden of infectious disease studies in Europe and the United Kingdom: a review of methodological design choices

List of AuthorsCharalampous Periklis, Haagsma Juanita A, Jakobsen Lea S, Gorasso Vanessa, Noguer Isabel, Padron-Monedero Alicia, Sarmiento Rodrigo, Santos João Vasco, McDonald Scott A, Plass Dietrich, Wyper Grant MA, Assuncao Ricardo, von der Lippe Elena, Adam Balázs, AlKerwi Ala'a, Arabloo Jalal, Baltazar Ana Lucia, Bikbov Boris, Borrell-Pages Maria, Brus Iris, Burazeri Genc, Chaintoutis Serafeim C, Chen-Xu José, Chkhaberidze Nino, Cilovic-Lagarija Seila, Corso Barbara, Cuschieri Sarah, Di Bari Carlotta, Dopelt Keren, Economou Mary, Emeto Theophilus I, Fantke Peter, Fischer Florian, Freitas Alberto, Garcia-Gonzalez Juan Manuel, Gazzelloni Federica, Gissler Mika, Gkitakou Artemis, Gulmez Hakan, Gunes Sezgin, Haller Sebastian, Haneef Romana, Hincapie Cesar A, Hynds Paul, Idavain Jane, Ilic Milena, Ilic Irena, Isola Gaetano, Kabir Zubair, Kamusheva Maria, Kolkhir Pavel, Konar Naime Meric, Kostoulas Polychronis, Kulimbet Mukhtar, La Vecchia Carlo, Lauriola Paolo, Levi Miriam, Majer Marjeta, Mechili Enkeleint A, Monasta Lorenzo, Mondello Stefania, Laguna Javier Muños, Nena Evangelia, Ng Edmond SW, Nguewa Paul, Niranjan Vikram, Nola Iskra Alexandra, O'Caoimh Rónán, Obradovic Marija, Pallari Elena, Peyroteo Mariana, Pinheiro Vera, Pranjic Nurka, Ortiz Miguel Reina, Riva Silvia, Santoso Cornelia Melinda Adi, Milicevic Milena Santric, Schmitt Tugce, Speybroeck Niko, Sprugel Maximilian, Steiropoulos Paschalis, Stevanovic Aleksandar, Thygesen Lau Caspar, Tozija Fimka, Unim Brigid, Uysal Hilal Bektas, Varga Orsolya, Vasic Milena, Vieira Rafael José, Yigit Vahit, Devleesschauwer Brecht, Pires Sara M


Publication year2023

JournalEpidemiology and Infection


Article number e19

Volume number151

Number of pages10




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This systematic literature review aimed to provide an overview of the characteristics and methods used in studies applying the disability-adjusted life years (DALY) concept for infectious diseases within European Union (EU)/European Economic Area (EEA)/European Free Trade Association (EFTA) countries and the United Kingdom. Electronic databases and grey literature were searched for articles reporting the assessment of DALY and its components. We considered studies in which researchers performed DALY calculations using primary epidemiological data input sources. We screened 3053 studies of which 2948 were excluded and 105 studies met our inclusion criteria. Of these studies, 22 were multi-country and 83 were single-country studies, of which 46 were from the Netherlands. Food- and water-borne diseases were the most frequently studied infectious diseases. Between 2015 and 2022, the number of burden of infectious disease studies was 1.6 times higher compared to that published between 2000 and 2014. Almost all studies (97%) estimated DALYs based on the incidence- and pathogen-based approach and without social weighting functions; however, there was less methodological consensus with regards to the disability weights and life tables that were applied. The number of burden of infectious disease studies undertaken across Europe has increased over time. Development and use of guidelines will promote performing burden of infectious disease studies and facilitate comparability of the results.

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Last updated on 2023-16-08 at 15:17