Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2)
Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives
Julkaisun tekijät: Belibasakis Georgios N., Belstrøm Daniel, Eick Sigrun, Gursoy Ulvi K., Johansson Anders, Könönen Eija
Kustantaja: WILEY
Julkaisuvuosi: 2023
Journal: Periodontology 2000
Tietokannassa oleva lehden nimi: PERIODONTOLOGY 2000
Lehden akronyymi: PERIODONTOL 2000
Sivujen määrä: 17
ISSN: 0906-6713
eISSN: 1600-0757
DOI: http://dx.doi.org/10.1111/prd.12473
Verkko-osoite: https://onlinelibrary.wiley.com/doi/10.1111/prd.12473
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/178885581
This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis-centered interpretation. Reference is made to anerobic microbiology and to the discovery of select periodontal pathogens and their virulence factors, as well as to biofilms. The evolution of contemporary molecular methods and high-throughput platforms is highlighted in appreciating the breadth and depth of the periodontal microbiome. Finally clinical microbiology is brought into perspective with the contribution of different microbial species in periodontal diagnosis, the combination of microbial and host biomarkers for this purpose, and the use of antimicrobials in the treatment of the disease.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
