The introductory chapter starts by referring to three topical examples of transformations in higher education that can be observed from a geopolitical perspective and, thus, provide a thematic entry point for the theme of the Volume: how at various levels – supranational, national, local, but also at the level of the firms or individuals – a premium has been placed on knowledge and knowledge generation activities and have been made centerpiece in imaginations of the future, in social, political and economic terms. Innovation, science capacity and education – representing the main missions of Higher Education – thus are reckoned key to succeeding in global economic competition. The Introduction discusses a geopolitical perspective on the transformations in higher education adopted in the chapters collected in this book, also relating the topic to adjacent debates in higher education research. Finally, the introduction provides a brief overview over the chapters of the book.