A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Associations of sedentary time, physical activity, and fitness with muscle glucose uptake in adults with metabolic syndrome
Tekijät: Garthwaite Taru, Sjöros Tanja, Laine Saara, Koivumäki Mikko, Vähä-Ypyä Henri, Eskola Olli, Rajander Johan, Kallio Petri, Saarenhovi Maria, Löyttyniemi Eliisa, Sievänen Harri, Houttu Noora, Laitinen Kirsi, Kalliokoski Kari, Vasankari Tommi, Knuuti Juhani, Heinonen Ilkka
Kustantaja: Wiley
Julkaisuvuosi: 2023
Journal: Scandinavian Journal of Medicine and Science in Sports
Tietokannassa oleva lehden nimi: Scandinavian journal of medicine & science in sports
Lehden akronyymi: Scand J Med Sci Sports
Vuosikerta: 33
Numero: 3
Aloitussivu: 353
Lopetussivu: 358
ISSN: 0905-7188
eISSN: 1600-0838
DOI: https://doi.org/10.1111/sms.14287
Verkko-osoite: https://doi.org/10.1111/sms.14287
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/177913291
Objective: The objective of the study was to investigate the associations of sedentary time, physical activity, and cardiorespiratory fitness with skeletal muscle glucose uptake (GU).
Methods: Sedentary time and physical activity were measured with accelerometers and VO2 max with cycle ergometry in 44 sedentary adults with metabolic syndrome. Thigh muscle GU was determined with [18 F]FDG-PET imaging.
Results: Sedentary time (β = -0.374), standing (β = 0.376), steps (β = 0.351), and VO2 max (β = 0.598) were associated with muscle GU when adjusted for sex, age, and accelerometer wear time. Adjustment for body fat-% turned all associations non-significant.
Conclusion: Body composition is a more important determinant of muscle GU in this population than sedentary time, physical activity, or fitness.
Ladattava julkaisu This is an electronic reprint of the original article. |