A1 Refereed original research article in a scientific journal
Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump
Authors: Rantanen Matias, Yousif Rizgar, Kallioinen Minna, Hynninen Ville-Veikko, Peltoniemi Marko, Söderholm Oki, Saarikoski Tuukka, Anttila Vesa, Aittokallio Jenni
Publisher: Elsevier
Publication year: 2022
Journal: Annals of Medicine and Surgery
Article number: 104812
Volume: 84
eISSN: 2049-0801
DOI: https://doi.org/10.1016/j.amsu.2022.104812
Web address : https://www.sciencedirect.com/science/article/pii/S2049080122015722
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/177190198
Objectives
To determine whether surgical technique has an effect on prognosis in coronary artery bypass grafting (CABG).
DesignRetrospective observational.
SettingSingle center.
ParticipantsAll the off-pump (OPCABG) and on-pump (ONCABG) patients at Turku University Central Hospital in 2018.
InterventionsNone.
Measurements and main resultsAfter propensity score matching, perioperative, 1-year and 3-year mortality did not differ between the groups. The ONCABG patients received more allogenic red blood cells (1.3 vs. 0.6 units, p = 0.020), autologous red blood cells (564 vs. 285 ml, p < 0.001) and crystalloids (3388 vs. 2808 ml, p < 0.001), and had higher postoperative values of troponin T (581 vs. 222, p = 0.001) and lactate (1.69 vs. 1.23, p < 0.001) than the OPCABG patients.
ConclusionsThe both techniques seem equally safe. However, there may be some benefits to avoiding using a heart-lung machine, such as lower infused fluid volumes. Myocardial damage may also be milder and postoperative hemodynamics more balanced in OPCABG patients, based on lower levels of troponin T and lactate.
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