A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
Using personalized prognosis in the treatment of relapsing multiple sclerosis: A practical guide
Tekijät: Van Wijmeersch Bart, Hartung Hans-Peter, Vermersch Patrick, Pugliatti Maura, Pozzilli Carlo, Grigoriadis Nikolaos, Alkhawajah Mona, Airas Laura, Linker Ralf, Oreja-Guevara Celia
Kustantaja: FRONTIERS MEDIA SA
Julkaisuvuosi: 2022
Journal: Frontiers in Immunology
Tietokannassa oleva lehden nimi: FRONTIERS IN IMMUNOLOGY
Lehden akronyymi: FRONT IMMUNOL
Artikkelin numero: 991291
Vuosikerta: 13
Sivujen määrä: 13
ISSN: 1664-3224
DOI: https://doi.org/10.3389/fimmu.2022.991291
Verkko-osoite: https://www.frontiersin.org/articles/10.3389/fimmu.2022.991291/full
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/176943213
The clinical course of multiple sclerosis (MS) is highly variable among patients, thus creating important challenges for the neurologist to appropriately treat and monitor patient progress. Despite some patients having apparently similar symptom severity at MS disease onset, their prognoses may differ greatly. To this end, we believe that a proactive disposition on the part of the neurologist to identify prognostic "red flags" early in the disease course can lead to much better long-term outcomes for the patient in terms of reduced disability and improved quality of life. Here, we present a prognosis tool in the form of a checklist of clinical, imaging and biomarker parameters which, based on consensus in the literature and on our own clinical experiences, we have established to be associated with poorer or improved clinical outcomes. The neurologist is encouraged to use this tool to identify the presence or absence of specific variables in individual patients at disease onset and thereby implement sufficiently effective treatment strategies that appropriately address the likely prognosis for each patient.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
