The mechanism of macroautophagy: The movie
: Reggiori Fulvio, Boya Patricia, da Costa David, Elazar Zvulun, Eskelinen Eeva-Liisa, Farrés Judith, Guettler Sebastian, Kraft Claudine, Jungbluth Heinz, Martinez Ana, Morel Etienne, Pless Ole, Proikas-Cezanne Tassula, Simonsen Anne
Publisher: Taylor & Francis
: 2022
: Autophagy Reports
: 1
: 1
: 414
: 417
DOI: https://doi.org/10.1080/27694127.2022.2096115
: https://doi.org/10.1080/27694127.2022.2096115
: https://research.utu.fi/converis/portal/detail/Publication/176657316
This animated movie presents the mechanism of macroautophagy, hereafter autophagy, by showing the molecular features of the formation of autophagosomes, the hallmark organelle of this intracellular catabolic pathway. It is based on our current knowledge and it also illustrates how autophagosomes can recognize and eliminate selected cargoes.